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The properties that determine the anti-infective action of lipids are related to their structure: e.g., monoglycerides, free fatty acids. The monoglycerides are active; diglycerides and triglycerides are inactive. Of the saturated fatty acids, lauric acid has greater antiviral activity than either caprylic acid (C-8), capric acid (C-10), or myristic acid (C-14). In general, it is reported that the fatty acids and monoglycerides produce their killing/inactivating effect by lysing the plasma membrane lipid bilayer. The antiviral action attributed to monolaurin is that of solubilizing the lipids and phospholipids in the envelope of the virus, causing the disintegration of the virus envelope. However, there is evidence from recent studies that one antimicrobial effect in bacteria is related to monolaurin's interference with signal transduction (Projan et al 1994), and another antimicrobial effect in viruses is due to lauric acid's interference with virus assembly and viral maturation (Hornung et al 1994).

Recognition of the antiviral aspects of the antimicrobial activity of the monoglyceride of lauric acid (monolaurin) has been reported since 1966. Some of the early work by Hierholzer and Kabara (1982) that showed virucidal effects of monolaurin on enveloped RNA and DNA viruses was done in conjunction with the Center for Disease Control of the U.S. Public Health Service. These studies were done with selected virus prototypes or recognized representative strains of enveloped human viruses. The envelope of these viruses is a lipid membrane, and the presence of a lipid membrane on viruses makes them especially vulnerable to lauric acid and its derivative monolaurin.

The medium-chain saturated fatty acids and their derivatives act by disrupting the lipid membranes of the viruses (Isaacs and Thormar 1991; Isaacs et al 1992). Research has shown that enveloped viruses are inactivated in both human and bovine milk by added fatty acids and monoglycerides (Isaacs et al 1991), and also by endogenous fatty acids and monoglycerides of the appropriate length (Isaacs et al 1986, 1990, 1991, 1992; Thormar et al 1987).

Some of the viruses inactivated by these lipids, in addition to HIV, are the measles virus, herpes simplex virus-1 (HSV-1), vesicular stomatitis virus (VSV), visna virus, and cytomegalovirus (CMV). Many of the pathogenic organisms reported to be inactivated by these antimicrobial lipids are those known to be responsible for opportunistic infections in HIV-positive individuals. For example, concurrent infection with cytomegalovirus is recognized as a serious complication for HIV+ individuals (Macallan et al 1993). Thus, it would appear to be important to investigate the practical aspects and the potential benefit of an adjunct nutritional support regimen for HIV-infected individuals, which will utilize those dietary fats that are sources of known antiviral, antimicrobial, and antiprotozoal monoglycerides and fatty acids such as monolaurin and its precursor lauric acid.

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What users are saying about Coconut Oil Supreme™

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I'm back to buying the best! I tried another brand coconut oil brand claiming to be "virgin" and highest quality - it was TERRIBLE & tasted like soap!! I forced myself to choke down 16oz before relegating the rest to cooking oil status. Just *thinking* about making my morning "butter coffee" with your sweet coconut oil supreme again makes me feel happy! Though I thought to save $, it ended up being a costly mistake & hard-to-swallow lesson! C.B.

Bought several coconut oils from health food stores. Although they were organic, the smell and taste were awful and had to throw them out. When I saw the sample size of coconut supreme I thought it was perfect to try first before spending money on a product I wasn't sure of. (customer who first bought sample.) M.S.

I am a nurse, I had a patient a few nights ago who let me use some of her coconut oil supreme after I commented on how nice her lotion smelled. She wanted me to get an extra medication cup and fill it with a few scoops to take home and try. I love how it moisturizes my over dry over washed nursing hands. I am going to try it in my dog's food also, he is always itchy. I will let you know! I am also purchasing a jar for my mother who has a lot of allergies to products. Thanks!! A.D.

My husband and I love this product! We've tried other coconut oils and none of them match the quality and taste. We also love that it is available in such a large quantity! S.S.

I am ordering these two samples and having them sent to one of my dearest friends because I want her to try these two products. I have become a walking 'advertisement' for Coconut Oil Supreme!! ... I am a repeat customer because I love, love, love your products! D. W.

This is my second order. Yours is the first Coconut Oil I have tried, but I can't imagine any other company's product being better. Your Cococnut Oil Supreme has such a delicate flavor. I use it now also as a skin moisturizer and have fallen in love with it's ultra-light fragrance. Wish I had discovered your company sooner! Linda D.

You offer the best selection with the highest quality. I love this company ...I've been a long time customer and absolutely love your products. I highly recommend to anyone who asks. You're the best out there. For me quality far exceeds the cost! S.N.

You carry the absolute best coconut based products available, and your coconut oil is head and shoulders better than any other oil available. S.J.

Thanks for your good work in making this good oil available online... I luv the coconut oil from your store -- its clarity and and smooth consistency (almost like water), fresh natural taste and mild fragrance, and quality is the best one I've found... it's the best of the best!! A regular / longtime customer now, Sharon S.

Just wanted to say I love your coconut oil. I have been trying several brands and I bought a small quantity from each. I noticed how crystal clear your oil is when it's in its melted state. The other oils were yellow, cloudy or just disgusting looking. Thanks for a great product and will be ordering again soon. M.S.

You have the most delicious tasting coconut oil I have ever tasted. I tried 5 different brands. You're the best!

Fabulous product - much better flavor than other oil available.

Now I know what real coconut oil should taste like.

Thank you for being a great source for the best oil on earth!

Thank you for your great product and wonderful service.

Tried them all and yours is the best.

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